Mascot (software)

Mascot
Stable release 2.3
Type Protein identification
License proprietary
Website http://www.matrixscience.com/

Mascot is a software search engine that uses mass spectrometry data to identify proteins from primary sequence databases.[1][2]

Many research facilities utilize Mascot, either by private or public server for database searching.

Mascot incorporates code from MOWSE, developed by Darryl Pappin and David Perkins at the Imperial Cancer Research Fund, and licensed from Cancer Research Technology.

The performance of many mass spectrometry software, including Mascot, can be observed in the 2011 iPRG study.

References

  1. ^ Perkins DN, Pappin DJ, Creasy DM, Cottrell JS (December 1999). "Probability-based protein identification by searching sequence databases using mass spectrometry data". Electrophoresis 20 (18): 3551–67. doi:10.1002/(SICI)1522-2683(19991201)20:18<3551::AID-ELPS3551>3.0.CO;2-2. PMID 10612281. 
  2. ^ Koenig T, Menze BH, Kirchner M, et al. (September 2008). "Robust prediction of the MASCOT score for an improved quality assessment in mass spectrometric proteomics". J. Proteome Res. 7 (9): 3708–17. doi:10.1021/pr700859x. PMID 18707158.